Products and Services |SAR IVM-Sup

Product Description

SAR IVM Supreme medium (Catalog#: SAR IVM-Sup 01, 02) is Simple and Reliable (SAR) medium for oocyte maturation in vitro (IVM).  It is specifically designed for a bovine in vitro fertilization (IVF) process.  A high blastocyst development rate is guaranteed.  This medium is developed with Renova Life Inc. (RLI) standardized recipes that have been proven to be perfectly suitable for in vitro production of bovine embryos in several peer-reviewed publications. Years of our research and experience have been put into the development of this medium, offering you the best quality and performance for IVM/IVF/IVC. Specifically tested embryo-water and embryo-bovine serum albumin (BSA) are used in our RLI in-house SAR IVM/IVF/IVC products, which have been well tested for bovine IVF and embryo culture in vitro and for making IVF and OPU-IVF embryos for cryopreservation and embryo transfer practices.   

RLI SAR IVM-Sup medium is a constant high quality product, ideal for oocyte maturation and production of embryos in vitro.  It is prepared for commercial and research use. RLI SAR IVM-Sup medium has been prepackaged as follows: SAR IVM-Sup 01, 1 mL/vial, 5 vials; SAR IVM-Sup 02, 4 mL/vial, 5 vials.

SAR IVM-Sup contains Medium 199 (M199) with Earle’s salts, L-glutamine, sodium bicarbonate, and HEPES, supplemented with 10% (v/v) fetal calf serum, 0.5 µg/mL ovine FSH, 5.0 µg /mL ovine LH and 1.0 µg /mL estradiol, cytokines and other specific small molecules that greatly promote oocyte maturation in vitro. This maturation medium is particularly used for IVF with the semen from low fertility bulls, with an increase of 15-20 % blastocyst rate higher than that with regular IVM medium, and up to 55-60% blastocyst rate based on oocytes and high fertility bull semen used for IVF.

Storage temperature:  Store at -20 °C upon arrivalExpiration: 2 months after production date.

Expiration date: 2 months after production date.


For more information about SAR IVM-Sup, please visit


For Animal Use Only



Bovine IVF Embryo Production. Bovine cumulus-oocyte complexes were collected by OPU from donor animals (A), and matured for 22-24h with SAR IVM prior to IVF (B), showing expanding of cumulus cells. The embryos cleaved to 8-celled stage after 44 h culture in vitro (C), and they developed to blastocyst stage on Day 7 (D). Oocytes were fertilized in our serum-free SAR IVF medium containing 6 mg/mL BSA-embryo under a condition of  5%O2, at 39°C for 18 hours. Embryos then were cultured in our SAR IVC serum-free medium containing 6 mg/mL BSA-embryo under a condition of mixed gases of 5%CO2, 5%O2, and 90%N2, at 39°C for 7days.


Ordering Information

Cat # SAR IVM-Sup 01:   1 mL/vial, 5 vials        $100.00 plus S&H


Cat # SAR IVM-Sup 02:   4 mL/vial, 5 vials        $315.00 plus S&H


You can place your order by phone (904-379-6507) or fax (301-576-5078).
You can also send your inquires following this link.
Thank you for your business.

Product Flyer (pdf format)


Product Description (pdf format)


Shipping and Return policy

Products and Services | SAR IVM